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19# Development of Head, Neck, Eye & Ear
1. Pharyngeal membranes are formed by which germ layers?
Mesoderm only
Ectoderm and mesoderm
Ectoderm and endoderm with mesoderm in between
Endoderm only
Explanation:
Pharyngeal membranes are double-layered (ectoderm + endoderm) with mesoderm between them.
2. Pharyngeal arches begin to develop during which embryonic week?
Third week
Fourth week
Fifth week
Sixth week
Explanation:
Pharyngeal arches develop early in the fourth week as neural crest cells migrate.
3. Which pharyngeal arch is rudimentary and not visible externally?
Second
Third
Fourth
Fifth
Explanation:
The fifth pharyngeal arch is rudimentary and not visible on the embryo surface.
4. A typical pharyngeal arch contains all EXCEPT:
Lymphatic vessel
Arch artery
Cartilaginous rod
Cranial nerve
Explanation:
Each arch contains an artery, cartilage, muscle component, and a nerve — not lymphatics.
5. Pharyngeal arches support the lateral walls of which structure?
Primitive larynx
Stomodeum
Primordial pharynx
Neural tube
Explanation:
Pharyngeal arches support the lateral walls of the primordial pharynx.
6. Neural crest cells mainly contribute to which component of the pharyngeal arch?
Endodermal lining
Ectodermal covering
Arch arteries
Mesenchymal core
Explanation:
Neural crest cells migrate into the arches and form most of the mesenchymal core.
7. Which ossicles develop from the first pharyngeal arch cartilage?
Stapes only
Malleus and incus
Incus and stapes
All auditory ossicles
Explanation:
The dorsal end of Meckel cartilage (1st arch) forms malleus and incus.
8. The mandible develops by which mechanism?
Endochondral ossification
Direct cartilage ossification
Intramembranous ossification
Periosteal ossification
Explanation:
The mandible forms by intramembranous ossification around Meckel cartilage.
9. The stapes and styloid process are derived from which pharyngeal arch?
Second
First
Third
Fourth
Explanation:
Second arch cartilage gives rise to stapes and styloid process.
10. Which structure forms the greater cornu of the hyoid bone?
Second arch cartilage
Fourth arch cartilage
Hypopharyngeal eminence alone
Third arch cartilage
Explanation:
The third arch cartilage forms the greater cornu of the hyoid bone.
11. The epiglottis develops from which structure?
Fourth arch cartilage
Sixth arch cartilage
Hypopharyngeal eminence
Meckel cartilage
Explanation:
The epiglottis develops from the hypopharyngeal eminence.
12. Which muscle is derived from the third pharyngeal arch?
Stylopharyngeus
Cricothyroid
Stapedius
Tensor veli palatini
Explanation:
Stylopharyngeus is the only muscle derived from the third arch.
13. All intrinsic laryngeal muscles EXCEPT cricothyroid are derived from:
Fourth arch
Sixth arch
Third arch
Second arch
Explanation:
Sixth arch gives rise to intrinsic laryngeal muscles except cricothyroid.
14. The nerve of the first pharyngeal arch is:
Facial nerve
Glossopharyngeal nerve
Vagus nerve
Trigeminal nerve
Explanation:
The trigeminal nerve supplies the first pharyngeal arch.
15. Muscles of facial expression are derived from which arch?
Second
First
Third
Fourth
Explanation:
Second arch gives rise to muscles of facial expression.
16. Which nerve supplies the fourth pharyngeal arch?
Recurrent laryngeal nerve
Glossopharyngeal nerve
Superior laryngeal nerve
Hypoglossal nerve
Explanation:
The superior laryngeal branch of the vagus supplies the fourth arch.
17. The recurrent laryngeal nerve is the nerve of which arch?
Fourth
Sixth
Third
Second
Explanation:
The recurrent laryngeal nerve supplies derivatives of the sixth arch.
18. Cricothyroid muscle is supplied by:
Recurrent laryngeal nerve
Facial nerve
Glossopharyngeal nerve
Superior laryngeal nerve
Explanation:
Cricothyroid is derived from the fourth arch and supplied by the superior laryngeal nerve.
19. Which prominence gives rise to maxillary and mandibular components of the face?
First pharyngeal arch
Second pharyngeal arch
Frontonasal prominence
Hypopharyngeal eminence
Explanation:
The first arch forms maxillary and mandibular prominences.
20. Failure of neural crest migration into pharyngeal arches most severely affects:
Limb muscles
Spinal cord development
Face and neck structures
Somite formation
Explanation:
Neural crest cells are essential for development of facial and neck structures.
21. The body of the hyoid bone develops from:
Second arch cartilage
Hypopharyngeal eminence
Third arch cartilage alone
Fourth arch cartilage
Explanation:
The body of the hyoid bone develops from the hypopharyngeal eminence.