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3# Vascular Diseases of CNS II

1. The most characteristic presenting symptom of subarachnoid hemorrhage is:

Sudden severe “worst headache of life”
Progressive focal neurological deficit
Gradual loss of consciousness
Isolated seizures
Explanation:
Subarachnoid hemorrhage classically presents with a sudden, severe “thunderclap” headache.

2. Xanthochromia in CSF indicates:

Acute bacterial meningitis
Traumatic lumbar puncture
Subarachnoid hemorrhage
Intraventricular tumor
Explanation:
Xanthochromia reflects breakdown of blood in CSF and is typical of subarachnoid hemorrhage.

3. The most serious acute complication of subarachnoid hemorrhage occurring about 1 week later is:

Re-bleeding
Hydrocephalus
Cerebral edema
Vasospasm leading to infarction
Explanation:
Vasospasm peaks at about 1 week and can cause secondary ischemia and infarction.

4. Re-bleeding after subarachnoid hemorrhage is most likely during:

First 24 hours
First 2 weeks
After 1 month
After 6 months
Explanation:
Risk of re-bleeding is highest in the first 2 weeks and is associated with increased mortality.

5. Communicating hydrocephalus following subarachnoid hemorrhage is caused by:

Aqueductal stenosis
Intraventricular clot
Fibrosis of leptomeninges
Brain edema
Explanation:
Fibrosis of leptomeninges leads to sluggish CSF flow and chronic communicating hydrocephalus.

6. The most common congenital vascular abnormality of the brain is:

Arteriovenous malformation
Cavernous hemangioma
Capillary telangiectasia
Venous angioma
Explanation:
AVMs are the most common congenital vascular malformations of the CNS.

7. Gliotic brain tissue between abnormal vessels is characteristic of:

Cavernous hemangioma
Capillary telangiectasia
Venous angioma
Arteriovenous malformation
Explanation:
AVMs show abnormal arteries and veins with intervening gliotic brain tissue.

8. Dilated thin-walled vascular channels without intervening brain tissue describe:

AVM
Cavernous hemangioma
Berry aneurysm
Capillary telangiectasia
Explanation:
Cavernous hemangiomas consist of thin-walled vascular channels without brain tissue between them.

9. The source of bleeding in epidural hematoma is usually:

Bridging veins
Cortical veins
Middle meningeal artery
Superior sagittal sinus
Explanation:
Epidural hematoma results from rupture of the middle meningeal artery.

10. The classic clinical course of epidural hematoma includes:

Lucid interval followed by rapid loss of consciousness
Immediate coma
Slow progressive dementia
Recurrent seizures only
Explanation:
A lucid interval followed by rapid deterioration is classic for epidural hematoma.

11. Subdural hematoma most commonly results from rupture of:

Middle meningeal artery
Cortical arteries
Venous sinuses
Bridging veins
Explanation:
Subdural hematomas result from disruption of bridging veins.

12. Chronic subdural hematoma is most commonly seen in:

Young athletes
Elderly patients with brain atrophy
Patients with skull fractures
Patients with AVMs
Explanation:
Brain atrophy stretches bridging veins, predisposing elderly patients to chronic subdural hematoma.

13. Which feature best distinguishes epidural from subdural hematoma?

Presence of headache
Raised intracranial pressure
Lucid interval
History of trauma
Explanation:
A lucid interval followed by rapid deterioration is characteristic of epidural hematoma.

14. Concussion is best defined as:

Reversible functional brain disturbance without structural lesion
Diffuse axonal injury
Cortical contusion
Intracerebral hemorrhage
Explanation:
Concussion causes temporary altered consciousness with no demonstrable lesion.

15. Contrecoup injuries occur due to:

Direct impact at site of trauma
Penetrating head injury
Local vascular rupture
Rotational and deceleration forces
Explanation:
Contrecoup injuries occur opposite the site of impact due to rotational and deceleration forces.

16. Diffuse axonal injury primarily affects:

Cortex only
White matter at grey–white junction
Basal ganglia
Brainstem nuclei only
Explanation:
DAI affects white matter tracts, especially at the grey–white matter junction.

17. Retraction balls are characteristic of:

Concussion
Cortical contusion
Diffuse axonal injury
Subdural hematoma
Explanation:
Retraction balls represent swollen disrupted axons seen in diffuse axonal injury.

18. A patient with post-traumatic coma and later vegetative state most likely has:

Epidural hematoma
Subarachnoid hemorrhage
Cortical contusions
Diffuse axonal injury
Explanation:
Diffuse axonal injury commonly leads to prolonged coma and vegetative state.

19. A cervical spinal cord injury above C4 results in:

Paralysis of the diaphragm
Paraplegia
Loss of bladder control only
Quadriplegia with intact respiration
Explanation:
Injury above C4 paralyzes the diaphragm, leading to respiratory failure.

20. A typical long-term complication of spinal cord trauma is:

Migraine
Ascending and descending tract degeneration
Hydrocephalus
Cerebral vasospasm
Explanation:
Spinal cord injury leads to ascending and descending degeneration of nerve tracts with systemic complications.